Interferon Alpha Treatment and Endocrine Disease

[Interferon-alpha: a endocrine disruptor?].

Endocrine-Manifestations of Cirrhosis and Liver Disease

The liver is involved in the synthesis and metabolism of many kinds of hormones, various abnormalities hormone levels are found in advanced liver disease. For example the liver is, extremely sensitive to changes in insulin or glucagon levels. The liver is the primary organ of iron storage is frequently involved, diabetes is common in patients with iron overload and may be seen in cirrhosis. Chr...

[Treatment of lymphangioma with alpha-2a-interferon]

OBJECTIVE: To describe the results of the use of alpha-2a-interferon in the treatment of inoperable childhood lymphangiomas refractory to other therapeutic management. METHOD: We reviewed the literature about pathogenic events and the treatments available for lymphangiomas. Based on that, we used alpha-2a-interferon at a dose of 3 million units/m(2)/day administered subcutaneously to patients w...

Anti-interferon alpha treatment in SLE.

Several studies in the last decade have highlighted the role of the type I interferon (IFN-I) pathway, and particularly interferon alpha (IFNα) in SLE pathogenesis. As a result, a multitude of potential treatments targeting IFNα have emerged in the last few years, a few of which have already completed phase II clinical trials. Some of the treatment strategies have focused on blocking IFNα or it...

Bipolar disorder associated with interferon-alpha treatment.

Accepted 9 July 1997 Interferon-alpha (Hoffman-La Roche Ltd, Basel, Switzerland) is a highly purified, bacterially synthesized agent with antiviral, antiproliferative and immunomodulatory properties.' Interferon-alpha has been approved for the treatment of several types of cancer (eg, leukaemia, lymphoma, renal cell carcinoma and melanoma) and of chronic hepatitis.2'4 Usually causing flu-like s...